- 1 Area 1: Dwelling
- 2 Area 2-a: Jungle
- 3 Area 2-b: Volcana
- 4 Area 3: Olmec's Lair
- 5 Area 4-a1: Tide Pool
- 6 Area 4-a2: Abzu
- 7 Area 4-b1: Temple of Anubis
- 8 Area 4-b2: The City of Gold
- 9 Area 4-b3: Duat
- 10 Area 5: Ice Caves
- 11 Area 6-a: Neo Babylon
- 12 Area 6-b: Tiamat's Throne
- 13 Area 7-a: Sunken City
- 14 Area 7-b: Eggplant World
- 15 Area 7-c: Hundun's Hideaway
- 16 Area 7-d: Cosmic Ocean
Area 1: Dwelling
The Dwelling is the first of the 16 available areas. It gets its name from Quillback and his many Caveman underlings who make their home here. Although it is the first area in the game, it will easily dispatch of careless delvers as they continue forwards.
Area 2-a: Jungle
Plant life like climbable trees and vines flourish here, and as a returning area from Spelunky HD, one can encounter some old enemies such as Mantraps and Tiki Men, while encountering brand new threats like Witch Doctors and Spear Traps.
Area 2-b: Volcana
It is analogous to Spelunky HD's Hell, being a place filled with fire and brimstone, even featuring enemies who moved here from Hell, such as Imps and Vlad. Unlike Hell however, it has much more mechanical aesthetics; Drills, Robots, and other industrial mining related features litter the cooler sections of the area.
Area 3: Olmec's Lair
The first of the boss worlds where the player fight the namesake Olmec, returning from Spelunky Classic and Spelunky HD with a few new tricks up his sleeve.
It's a large, fairly empty space with three floors of thick stone brick and a massive lava lake at the bottom. If the player defeats Olmec by sinking him into the lava, they can use the top of his head to enter a sub area containing the Ankh.
Area 4-a1: Tide Pool
Area 4-a2: Abzu
Abzu is a tall arena with pillars, Jiangshi, and Jiangshi Assassins scattered about. Beneath the area is a bottomless trench of water and a hidden passage that lead to the top of the arena. Defeating Kingu near the top of the arena will cause her to drop the Tablet of Destiny.
Area 4-b1: Temple of Anubis
Area 4-b2: The City of Gold
The City of Gold is a place of legend, known for being made entirely of solid gold.
Players may blow up the city and loot the many Pots of Gold to obtain massive quantities of treasure while dodging deadly Giant Crush Traps and Croc Men, but may also offer themselves on the altar found in the center of the level while equipped with an Ankh to descend into the Duat.
Area 4-b3: Duat
Upon entering the Duat, the player will lose all of their items, lose their Ankh, and have their HP reset to 4, making the journey upwards more difficult. As they ascend, the player may encounter Apep along with numerous Ammit.
Area 5: Ice Caves
The Ice Caves is the fifth area of the game. Instead of being a set of 4 levels, it is instead one singular, very large level. It is where all crossroads converge, unifying all of the split paths in the game.
After completing the Ice Caves, the player will find themselves in Neo Babylon.
Area 6-a: Neo Babylon
Neo Babylon is the sixth world of Spelunky 2. It is an ancient city of the future where the Olmites reside.
As the Olmites continue to be locked in a bitter conflict with the Aliens, It is highly dangerous and filled to the brim with hazardous Laser and Spark Traps, crushing Elevators, and Forcefields. Bringing a flammable pack item like a Jetpack to Neo Babylon is especially dangerous, as it can be ignited and blown up easily by the igneous hazards created by Spark Traps and UFOs in the area.
Once the player completes 6-3, they will find themselves in Tiamat's Throne.
Area 6-b: Tiamat's Throne
The second boss area of Spelunky 2. It houses Tiamat on her throne, above an endlessly deep lake.
If the player defeats Queen Tiamat here, they may take the normal exit to achieve the normal ending, while above Tiamat's Throne is a massive gauntlet of Spark Traps and Forcefields, most easily passed with the help of the Qilin.
If the player chooses to ascend up this gauntlet and makes it to the top, they may enter the spaceship found there, taking them to the Sunken City.
Area 7-a: Sunken City
The Sunken City is accessed ascending Tiamat's Throne and taking the spaceship found at the top of the level.
It is an upside down Lovecraftian land that comes off as eerily and deceptively peaceful. It has it's own ecosystem of Frogs, Giant Flies, and their offspring. It is considered to be a spiritual successor to The Worm from Spelunky HD.
Players who successfully escort the Eggplant Child to the Mother Statue in 7-1 will be granted access to the Eggplant World. Completing 7-3 of the Sunken City will take the player to Hundun's Hideaway, occupying 7-4.
Area 7-b: Eggplant World
None of the creatures here in this eggplant-themed level can hurt the player; not even the Ghost will spawn to attack the player after enough elapsed time. King Yama can be found here as the Eggplant King. Numerous chunks of Eggplant Flesh and the Eggplant Crown can be obtained from killing him.
At the top of the level is an exit door that will take the player back to the Sunken City into level 7-3.
Area 7-c: Hundun's Hideaway
At the top of the level, a large arena can be found where the player fights Hundun and can either escape to complete the hard ending, or shoot his eye with the Arrow of Light from Hou Yi's Bow to enter the Cosmic Ocean.
Area 7-d: Cosmic Ocean
Each level is built from parts of every other area in the game, and loop around within itself in every direction. A Celestial Jelly blocks the exits to each level, and one must destroy three celestial orbs in each level to move the jelly out of the way.