Fire Frogs are very similar to regular frogs, but with one important difference - After being killed, their corpses will explode after a short delay.
While alive, they should just be dealt with exactly how you would a regular Blue Frog.
If a Fire Frog falls into a pool of any liquid (even in a primed state after being killed), it will be extinguished and turn into a regular blue Frog.[Needs Research] In doing so, a Fire Frog corpse that is about to explode may be revived as a living Blue frog, and must be killed again.[Needs Research]
Fire Frog corpses cannot be sacrificed to Kali at an Altar, and attempting this will merely destroy the altar and invite Kali's anger.[Needs Research]